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The concerns about the adverse effects of non-noble varieties, produced by their undesirable composition of kavalactones and high concentrations of potentially harmful compounds (flavokavains, which are not present in any significant concentration in the noble varieties), have led to legislation prohibiting exports from countries such as Vanuatu
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90 Taken together, these findings indicate that autophagy is involved in the occurrence and development of UC and that the inhibition of autophagy could be a therapeutic strategy for treating UC by alleviating intestinal inflammation
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