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Redox imbalance stress in diabetes mellitus: Role of the polyol pathway - PMC
Importantly, there is very little direct experimental evidence in support of this hypothesis, which is based on the assumption that the neurotoxicity is caused by similar mechanisms as described for hepatotoxicity [183]
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More recently, however, p53 has been shown to function as a tumor suppressor by directly modulating glucose metabolism through the transcription of mir-34A, a micro-RNA [157]
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