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Even with some of the more commonly associated side effects—like hair loss and skin changes—a lot of it is believed to be due to the rapid weight loss many patients experience when taking GLP-1 medication (up to 20% of their body weight over 72 weeks) rather than the drug itself
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While the expression of DNMT3B, DNMT3L, and TET1 is barely detectable in SCD erythroblasts, the expression of DNMT1, DNMT3A, TET2 or TET3 was not significantly changed at the mRNA or protein level after DMF treatment (Supplementary Fig
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