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This tutorial consists of four steps : Data curation ( alvaMolecule ) Molecular descriptors calculation ( alvaDesc ) Models development ( alvaModel ) Model application and test ( alvaRunner ) 1
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Interestingly, mammalian AceCS are regulated by reversible acetylation catalyzed by the sirtuins, SIRT1 and SIRT3, and the activity of PGC-1α is also regulated by SIRT1 activity
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