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Caspase-3, an important regulator of apoptotic responses, can undergo glutathionylation, leading to the inactivation of caspase-3 by GSSG in a dose- and time-dependent manner [25], suggesting that apoptosis can be regulated by glutathionylation
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Reactive oxygen species KEY FIGURE Highlights • Glucotoxicity impairs β-cell function via oxidative stress and mitochondrial dysfunction
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