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These disorders are broadly categorized into two classes: neurodegenerative diseases, e.g., Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD), caused by neuronal damage, and neuropsychiatric disorders (e.g., anxiety, migraine, epilepsy, depression), characterized by abnormalities in brain function [62]
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Na + -dependent transport uses the potential energy stored in Na + /potassium-ATPase to transport glutamine across transmembrane electrochemical gradients (28)
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